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一 | Researchers from the University of California's San Diego School of Medicine have found that gonorrhea, as unpleasant as it is, might be the reason that our grandparents even exist.,Humans are among the few species that continue to live after menopause, which might be because of the evolution-proven support that older women provide when it comes to raising children.,The new findings suggest that pressure from pathogens like gonorrhea developed human gene mutations that protected elderly people from cognitive decline and made sure they could live longer.,The discovery comes by comparing human and chimpanzee genomes. The comparison revealed that humans have their own unique version of the gene for CD33, a receptor in immune cells that plays an important role in binding to a type of sugar called sialic acid. Human cells are coated with it and it helps immune cells "recognize" other cells and not attack them.,"Somewhere along the evolutionary line, humans picked up an additional mutated form of CD33 that is missing the sugar-binding site," the authors said. "The mutated receptor no longer reacts to sialic acids on damaged cells and plaques, allowing the microglia to break them down. Indeed, higher levels of this CD33 variant were independently found to be protective against late-onset Alzheimer's.",It would seem that CD33 was selected by evolution for its survival advantages, later making sure that humans were able to have big families that represent several generations. All of this, albeit indirectly, thanks to gonorrhea.。 ドジャース・大谷翔平投手(31)が22日(日本時間23日)、アリゾナ州グレンデールのキャンプ地で二刀流調整を行った。 まずは投手としてライブBP(実戦形式の練習)に登板。今キャンプ2度目の実戦形式のマウンドでは、ベッツ、フリーマンから三振を奪うなど、2イニングを想定して33球を投げ、安打性の当たりは2本のみで2三振を奪った。その後はフリー打撃で打席に立ち、35スイングで5本が柵越えだった。 パドレス・松井裕樹投手(30)が左脚付け根を痛めて侍ジャパンを辞退することが濃厚になっていることについては「本人からも(連絡が)きましたし、もちろん悔しいと思いますけど、まずは軽症なことを祈っていますし、リハビリの段階でシーズンに早く戻ってこられるように応援はしています」と親交のある左腕の無事を願っていた。
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